Concordance Study of Case Definitions of Healthcare Associated Infections
The European Centre for Disease prevention and Control (ECDC); www.ecdc.europa.eu. ECDC will be the owner of all documentation, all data and databases produced, and all methodology accumulated through the activities commissioned by ECDC for this project.
STUDY ADMINISTRATIONProf. Dr. Petra GastmeierInstitute of Hygiene and Environmental HealthCharité University Medicine BerlinHindenburgdamm 27D-12203 BerlinGermany
STUDY ORGANIZATIONDr. Sonja HansenInstitute of Hygiene and Environmental HealthCharité University Medicine BerlinHindenburgdamm 27D-12203 BerlinGermany
DATABASE ADMINISTRATIONDr. Michael BehnkeInstitute of Hygiene and Environmental HealthCharité University Medicine BerlinD-Hindenburgdamm 2712203 BerlinGermany
Surveillance of nosocomial infections is a valuable measure to decrease healthcare associated infection (HCAI) rates. It seems to be in particular successful when the infection rates of the own institution can be compared with reference data. Across Europe the diagnosis of HCAI varies since some countries are using Centers for Disease Control and Prevention (CDC) definitions others use Hospitals in Europe Link for Infection Control through Surveillance (HELICS) definitions. A change in surveillance definitions (indipendently of the direction of the conversion of the definitions; either from CDC definitions or to HELICS definitions or vice versa) would cause a loss of continuity to previous data in the individual surveillance system and also may lead to problems in reorganizing the surveillance system. Therefore the knowledge about the extent of concordance between both sets of HCAI definitions is of high value to interpret surveillance data from the individual countries and to compare previous surveillance data with data collected following the introduction of the other set of definitions.
The study consists of three work packages (WP) and schedules including the following tasks and activities:
WP1: During a first meeting the working group with experts from at least 5 EU Member States or EEA/EFTA countries and 1 ECDC expert differences between HCAI case definitions of IPSE/HELICS and CDC/NHSN will be identified. A protocol to assess the concordance of case definitions (including their subcategories) will be developed.
WP2: A concordance study will be conducted in acute care hospitals of at least 5 EU Member States or EEA/EFTA countries. A pre-test of the study protocol will be organized in at least 2 countries. In a second meeting of the working group the protocol will be adapted according to the findings of the pretest. Final data collection tools will be defined. A standardized training material for hospital staff will be developed and practical organisation of the study will be discussed and planned.
WP3: The concordance between HCAI definitions will be analysed and reported. In a third meeting results and scientific communication strategy will be discussed. Working group members are asked to translate study document forms in their national language and distribute them to the participating hospitals. Local infection control personnel who is performing the surveillance has to be trained in diagnosing HCAI according to EU (IPSE/HELICS) and US (CDC/NHSN) definitions.
Working group member
Dr. Alexander Blacky
Clinical Department for Hospital Hygiene, Clinical Institute for Hygiene and Medical Microbiology
Medical University of Vienna, Spitalgasse 23, A-1090 Vienna, Austria
Dr. Ingrid Morales
Scientific Institute of Public Health, Rue Juliette Wytsmanstraat 14, BE-1050 Brussels; Belgium
Prof. Dr. Pascal Astagneau
C-CLIN Nord - Département de santé publique
Université Pierre & Marie Curie,
ParisVI Centre des Cordeliers,
15 rue de l'Ecole de Médecine
FR-75006 Paris, France
Dr. Emese Szilagyi
National Center for Epidemiology, Department of Hospital Epidemiology,
Gyáli út 2-6. HU-1097 Budapest, Hungary
Dr. Marie Luisa Moro
Agenzia Sanitaria Regione Emilia Romagna, Area di Programma Rischio Infettivo, IBologna, Italy
Dr. Mercedes Palomar
Department of Intensive Care, Hospital Vall d'Hebron, Ps. Vall dHebron, 119, E-08035 Barcelona; Spain
Dr. Christine Geffers
Prof. Dr. Petra Gastmeier
Institute of Hygiene
Charité University Medicine Berlin
D-12203 Berlin, Germany
Dr. Carl Suetens
European Centre for Disease Prevention and Control
SE-171 83 Stockholm, Sweden
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